01 - Generously season beef chunks with salt and freshly ground black pepper.
02 - Heat olive oil in a large Dutch oven over medium-high heat and brown beef in batches until evenly seared on all sides. Transfer to a plate.
03 - Add onion, carrots, and celery to the pot and cook for 6 to 8 minutes until softened. Stir in garlic and cook for 1 additional minute.
04 - Stir in tomato paste, cooking for 2 minutes. Pour in red wine to deglaze the pot, scraping up browned bits. Simmer for 2 to 3 minutes until slightly reduced.
05 - Return seared beef to the pot. Add crushed tomatoes, beef stock, dried oregano, dried thyme, bay leaves, and optional red pepper flakes. Stir to combine and bring to a gentle simmer.
06 - Cover pot and cook over low heat for 3 hours, stirring occasionally until beef is tender and sauce thickens. Remove excess fat by skimming the surface.
07 - Discard bay leaves. Use two forks to shred beef into sauce. Taste and adjust seasoning with additional salt and pepper as needed.
08 - Meanwhile, cook pappardelle in a large pot of salted boiling water until al dente. Reserve ½ cup pasta water, then drain pasta.
09 - Toss cooked pasta with the ragu, adding reserved pasta water as needed to adjust sauce consistency.
10 - Plate pasta topped with ragu. Garnish with freshly grated Parmigiano-Reggiano and chopped basil or parsley. Serve immediately.